Subject: Table 2: MRI Criteria for Brain Abnormality: Space and Time Dissemination
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Date: Fri, 2 May 2008 11:11:08 -0600

Table
2:

MRI Criteria for Brain Abnormality:
Space and Time
Dissemination

MRI lesions
disseminated in space:
At least three of the
following criteria must be met:

One
gadolinium-enhancing lesion or nine T2-hyperintense lesions if
there is no gadolinium-enhancing lesion

At least one
infratentorial lesion

At least one
juxtacortical lesion

At least
three periventricular lesions

MRI lesions
disseminated in time:
At least one criterion
must be met:

If MRI is
more than 3 months after clinical event, then a
gadolinium-enhancing lesion at a site different from the original
clinical event is sufficient; if there is no gadolinium
enhancement, then a follow-up scan is required (usually > 3
months later). A new T2 or gadolinium-enhancing lesion on this
second or subsequent MRI fulfills the requirement.

If first MRI scan occurs less than 3 months after the onset of
the clinical event, then a second scan > 3 months later showing
a new gadolinium-enhancing lesion fulfills requirement. If no
gadolinium enhancement is seen at this second scan, a further scan
not less than 3 months after the first scan that shows a new T2
lesion or an enhancing lesion will suffice.

Adapted from reference 6

Copyright 2002 The Cleveland Clinic
Foundation

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