From: Subject: Table 2: MRI Criteria for Brain Abnormality: Space and Time Dissemination Date: Fri, 2 May 2008 11:11:08 -0600 MIME-Version: 1.0 Content-Type: text/html; charset="iso-8859-1" Content-Transfer-Encoding: quoted-printable Content-Location: http://www.clevelandclinicmeded.com/medicalpubs/diseasemanagement/neurology/multsclerosis/table2ms.htm X-MimeOLE: Produced By Microsoft MimeOLE V6.00.2900.3198 Table 2: MRI Criteria for Brain Abnormality: Space = and Time Dissemination
Table=20 2:
MRI Criteria for Brain Abnormality:
Space and = Time=20 Dissemination

MRI lesions=20 disseminated in space:
At least = three of the=20 following criteria must be met:

  1. One=20 gadolinium-enhancing lesion or nine T2-hyperintense = lesions if=20 there is no gadolinium-enhancing lesion=20
  2. At least one=20 infratentorial lesion=20
  3. At least one=20 juxtacortical lesion=20
  4. At least=20 three periventricular lesions

MRI lesions=20 disseminated in time:
At least one = criterion=20 must be met:

  1. If MRI is=20 more than 3 months after clinical event, then a=20 gadolinium-enhancing lesion at a site different from the = original=20 clinical event is sufficient; if there is no gadolinium=20 enhancement, then a follow-up scan is required (usually = > 3=20 months later). A new T2 or gadolinium-enhancing lesion on = this=20 second or subsequent MRI fulfills the requirement.=20
  2. If first MRI scan occurs less than 3 months after the = onset of=20 the clinical event, then a second scan > 3 months later = showing=20 a new gadolinium-enhancing lesion fulfills requirement. If = no=20 gadolinium enhancement is seen at this second scan, a = further scan=20 not less than 3 months after the first scan that shows a = new T2=20 lesion or an enhancing lesion will suffice. =

 

Adapted from reference 6<= /TD>
Copyright 2002 The Cleveland Clinic=20 Foundation

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