This course is a detailed discussion on opioid abuse. We start by discussing the basics of opioid abuse and then transition to the current opioid epidemic, its origins, and impacts. With that foundation we will do a deep dive into how opioid abuse impacts different people from all cultures, backgrounds, and ages. In this course, we will focus specifically on veterans, Native Americans, prisoners, and the elderly. We will then end the course by discussing prevention and the way forward.