This course features the treatment recommendations for those in special populations including the homeless, those in the criminal justice system, women, and racial/ethnic minorities. Healthcare professionals need to be aware of specific treatment needs of such populations and make adjustments in their assessment, diagnosis, referral, and service provision. This course is chapters 6 through 8 of Substance Use Disorder Treatment for People With Co-Occurring Disorders, Treatment Improvement Protocol (TIP) Series, No. 42. This treatment protocol is offered by the Substance Abuse and Mental Health Services Administration (SAMHSA) and was updated in March 2020.